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08:00AM 07/05/2018 - 05:00PM 10/05/2018 Hội trường tầng 1 Sunwah Ulis, Tòa nhà Choi Culture ĐHQGHN, 144 Xuân Thủy, Cầu Giấy, Hà Nội

Workshop Program

“Development of Heparin and Heparan Sulfate Glycotherapeutics”

Hanoi, 7th-10th May 2018

Time

Sunday 6th May 2018

(location to be announced)

18:00

Welcome Dinner

Time

Monday 7th May 2018

1st Floor, Sunwah-Ulis room, Choi Culture Center Building

144 Xuan Thuy Street, Cau Giay District, Hanoi

8:00-8:30

Registration

8:30-9:00

Opening Ceremony

Section 1: Heparin and heparan sulfate in healthcare current and future applications

Chairman: Dr. Mark Skidmore and Assoc. Prof. Nguyen Thanh Hai

9:00-9:30

“Glycotherapeutics: from farm to patient”

Prof. Dave Fernig

9:30-9:40

Discussion

Section 2: Old and New clinical applications of Heparin and Heparan Sulfate: Regenerative medicine

Chairman: Dr. Mark Skidmore and Assoc. Prof. Nguyen Thi Thu Hoai

9.40-10.10

“HS in regenerative medicine”

Dr. Cathy Merry

10.10-10.20

Discussion

10.20-10.40

Coffee break

10.40-10.55

“Evaluating local effect of autologous platelet rich plasma therapy on chronic wounds”

Dr. Nguyen Thi Bich Phuong

10.55-11.00

Discussion

11.00-11.20

“New findings and potential use of Heparan Sulfate

in kidney disease”

Dr. Laura Ferreras

11.20-11.25

Discussion

11.25-11.45

Epidemiological characteristics and outcome of chronic wounds treated at the national institute of burns”

Dr. Tran Ngoc Diep (National Institute of Burn)

11.45-11.50

Discussion

11.50-12.10

“Self-Assembling Peptide Hydrogels as Fully-Defined, Tuneable Matrix Environments for Disease Modelling and Therapeutics Screening”

Dr. Jennifer Ashworth

12.10-12.15

Discussion

12.15-13.45

Lunch

Section 3: Anticoagulation

Chairman: Assoc. Prof. Nguyen Thi Thu Hoai and Dr. Becky Miller

13.45-14.05

Update on the clinical use and monitoring of heparin”

Assoc. Prof. Nguyen Thi Thu Hoai

14.05-14.10

Discussion

14.10-14.30

Biomedical perspectives of anticoagulation: utility, accreditation, quality”

Dr. Trish Procter

14.30-14.35

Discussion

14.35-15.50

Crossover between LMWH and UFH in patients with acute coronary syndrome undergoing PCI: Clinical case report.”

Dr. Chu Dung Si

14.50-14.55

Discussion

14.55-15.15

“A novel method for the comparison of N-dimensional datasets: An application to heparin purity analysis”

Dr. Joe Holman

15.15-15.20

Discussion

15.20-15.45

Coffee break

Section 4: Infectious disease therapeutics derived from heparin and HS

Chairman: Assoc. Prof. Nguyen Thi Thu Hoai and Dr. Becky Miller

15.45-16.15

Heparin-derived therapeutics for malaria, flu, Dengue and Zika virus”

Dr Mark Skidmore

16.15-16.20

Discussion

16.20-16.35

“Infectious diseases in Vietnam”

Dr. Bui Thi Thu Hoai

16.35-16.40

Discussion

16.40-17.15

Poster section and General Discussion

18.30

Dinner (location to be announced)

Time

Tuesday 8th May 2018

1st Floor, Sunwah-Ulis room, Choi Culture Center Building

144 Xuan Thuy Street, Cau Giay District, Hanoi

From animal to therapeutic

Chairman: Prof. Dr. Phan Tuan Nghia and Assoc. Prof. Pham Kim Dang

8.15-8.30

Registration

8.30-8.40

Opening remarks

Prof. David Fernig

8.40-9.00

By-product from pangasius in Vietnam

Dr. Truong Dinh Hoai

9.00-9.05

Discussion

9.05-9.25

The therapeutic potential of non-mammalian glycosaminoglycan libraries

Dr. Lynsay Hadfield

9.25-9.30

Discussion

9.30-9.50

Biogenesis of FGF8-binding Heparan Sulfate Motifs”

Dr. Nguyen Kim Nu Thao

9.50-9.55

Discussion

9.55-10.20

Coffee break

10.20-10.40

Investigating the Structure-Function Relationships of Heparin By-Products”

Dr. Sarah Taylor

10.40-10.45

Discussion

10.45-11.05

Investigation of protein structure and function using X-ray crystallography, NMR and Mass-spectrometry”

Dr. Nguyen Van Sang

11.05-11.10

Discussion

11.10-11.30

“Chromatography and mass spectrometry characterisation of heparan sulfate”

Dr. Becky Miller

11.30-11.35

Discussion

11.35-11.55

Determination of environmental contaminants using chromatography and mass spectrum”

Dr. Dao Thi Nhung

11.55-12.00

Discussion

12.00-13.45

Lunch

Integrative Sciences for Heparin and Heparan sulfate Development

Chairman: Prof. David Fernig

13.45-14.05

“In vitro evaluation of antiviral agents”

Dr. Le Thi Thuy Duong

14.05-14.10

Discussion

14.10-14.30

Enzymes to make heparin/heparan sulfate, compounds to inhibit

Dr. Krithika Ramakrishnan

14.30-14.35

Discussion

14.50-15.10

“Magnetic Nanoparticles for Biomedicine”

Dr. Le Trong Lu

5.10-15.15

Discussion

15.15-15.35

Coffee break

15.35-15.55

“Modulation of FGF-FGFR signalling revealed by fully defined heparan sulphate saccharides: evidence for critical sulphation motifs”

Emma Sery

15.55-16.00

Discussion

16.00-16.20

Investigation on bioactive constituents from Panax species”

Dr. Nguyen Huu Tung

16.20-16.25

Discussion

16.25-16.45

“Determination of anti-tuberculosis drugs by LC-MS/MS method”

Assoc. Prof. Bui Thanh Tung

16.45-16.50

Discussion

16.50-17.10

Prospect and application of oral heparin”

Dr. Tu Thi Thu Hien

17.10-17.30

General Discussion/ Roundtable

18.30

Dinner (location to be announced)

Time

Wednesday 9th May 2018

2nd Floor, Y1 Building, School of Medicine and Pharmacy

144 Xuan Thuy Street, Cau Giay District, Hanoi

8.30-9.00

Registration

9.00-9.30

Opening Remarks

Prof. David Fernig

Drafting Vietnam – UK reseach plans in glycotherapeutics

9.30-9.15

Aims and outcomes of the drafting session

9.15-10.30

Three interdisciplinary Groups, each led by a senior scientist, to develop research ideas in:

(1) Extraction, purification and analysis of heparin and HS from Pigs and sea food

(2) Defining requirements to be met for clinical use of heparin: quality control and comparison to current international standard.

(3) Identification of key health areas where development of non-anticoagulant heparin/HS likely to have a major benefit.

10.30-11.00

Coffee break

11.00-11.45

5 min presentations + 10 min questions by each Group

11.45-12.00

Roundtable discussion

12.00-14.00

Lunch

14.00-14.30

Round Table to establish (1) project areas and (2) likely capacity building and to form groups for drafting project outlines

14.30-16.00

Groups (3-6) with a senor mentor define project outlines at different levels

(1) Training for capacity building

(2) Career development of UK and Vietnamese ECRs

(3) Joint UK-Vietnam research programmes

16.00-16.30

5 min presentation by each group

16.30-17.00

General discussion

18.30

Dinner and closing remarks

Time

Thursday 10th May 2018

Visiting tour

9.00-10.00

Xuan Thuy Campus

10.00-11.30

Hoa Lac Campus

11.30-13.30

Lunch

11.30-16.30

Outdoor Activities and Team Building